Cosmetics

Towelette Preservative Challenge Test For Cosmetics

Many cosmetics and personal care products are now available in the form of pre-saturated towelettes or wipes. Like the majority of personal care products having an aqueous base, pre-saturated towelettes are susceptible to microbial contamination and require a preservation system to protect them from degradation. Cosmetics and personal care...

Read more...

USP 51 Antimicrobial Effectiveness Test

USP <51> is used to test preservative effectiveness. The number "<51>" refers to General Chapter 51 of the United States Pharmacopeia (USP) National Formulary. Chapter 51 describes in detail the USP method for preservative efficacy testing, sometimes called "preservative challenge testing." If you would like to learn more about the...

Read more...

USP <51> – Preservative Challenge Test

Introduction The USP Chapter 51 Preservative Challenge Test is the most common method used to gauge preservative effectiveness.  Much like a Preservative Challenge Screen, it is used to evaluate the effect of preservatives in cosmetics, personal care products, and drug products. Preservatives are antimicrobial ingredients that are added to aqueous...

Read more...

USP <61> – Microbial Enumeration Test

The USP <61> - Microbial Enumerations Test is a product safety test found in Chapter 61 of the United States Pharmacopeia. It is suggested for use by the FDA for pharmaceuticals as well as cosmetics and personal care products to ensure that a product's preparation complies with pre-set specifications...

Read more...

USP <61> Microbial Examination of Nonsterile Products

The US Pharmacopeial Convention (USP) has developed and maintains a compendium of several test methods, which are utilized by companies that produce drugs and cosmetics to ensure quality and product integrity. Individual chapters of the compendium - each detailing a different test method - are identified by the chapter...

Read more...

USP <62> – Test For Objectionable Microorganisms

The USP <62> Test for Specified Microorganisms, like the USP <61>, is a product safety test from the United States Pharmacopeia. The USP <62> test evaluates a product for the presence or absence of potential pathogens. USP <62> tests are necessary for cosmetic and personal products to determine that any...

Read more...

Preservative Challenge Screen

Preservative challenge testing is a fast and easy way to learn about the efficacy of your preservative system. Preservatives are ingredients used to protect a product from deterioration and help it perform as intended for the lifetime of the product. The efficacy of a preservative depends on the combination of the product's...

Read more...

Preservative Challenge Test

USP 51: Procedure at a Glance The Antimicrobial Effectiveness test method or USP 51 utilizes the following microorganisms Candida albicans (ATCC No. 10231), Aspergillus niger (ATCC No. 16404), Escherichia coli (ATCC No. 8739), Pseudomonas aeruginosa (ATCC No. 9027), and Staphylococcus aureus (ATCC No. 6538). The test product is inoculated with...

Read more...

Realtime Aesthetic Stability Test

Realtime Aesthetic Stability Testing is very similar to the accelerated aesthetic test in that it tests for all the same characteristics, however products tested in realtime are stored at room temperature or the product's recommended storage conditions for the full length of shelf life testing. Accelerated Testing is commonly used to screen...

Read more...

Freeze-Thaw Stability Testing

During transportation of cosmetic products, it is not uncommon for them to encounter extreme temperature conditions, such as freezing or overheating. Thus, it is necessary for cosmetic products to be able to withstand a certain degree of temperature changes in transport. Freeze-thaw cycle testing is a part of stability testing that allows...

Read more...

ISO 11930 – Preservative Effectiveness Test

The ISO 11930 - Preservative Challenge Test is a procedure for evaluating the antimicrobial protection of a product. Much like the USP <51>, it evaluates the activity of preservatives or other intrinsic characteristics of a product that help maintain the safety of a product by inhibiting the growth and...

Read more...

Ocular Irritation Test

The Ocular Irritation Test, much like the Dermal Irritation Test, uses a 3-dimensional model of eye tissue to determine the potential of a cosmetic product or ingredient to cause eye irritation when used by the consumer. Just as some cosmetic products can cause irritation to the skin, they can cause similar effects to the...

Read more...

Package Compatibility Testing

When testing a cosmetic or personal care product for shelf-life and stability, packaging is a major factor that should be taken into consideration. While the product itself may have a relatively stable shelf-life when tested in glass or another temporary package, the same stability may not be observed in...

Read more...

PCPC (formerly CTFA) Test Methods for Cosmetics

Cosmetics and personal care products are perfect environments for microorganisms to grow unless proper measures are taken during formulation and manufacture to preserve them. Cosmetics and personal care products are intended for use in direct contact with the body and this makes it imperative for these products to be...

Read more...

Photostability Testing

Cosmetic and personal care products may be exposed to many different conditions throughout their life cycle. When considering a stability testing regimen, it is necessary to try to replicate the conditions that they are most likely to experience during their transport, storage and use. When we go outside and our bodies are...

Read more...