STRUCTURE AND PHYSIOLOGY
Gardnerella vaginalis is a non-spore-forming, coccobacillary (intermediate shape between cocci and bacilli), non-motile bacterium. This microorganism possesses a very thin Gram-positive wall that can appear as either Gram-positive or Gram-negative when stained. G. vaginalis is a facultative anaerobe and is often found to proliferate with other anaerobic bacteria in the female genital tract.
TRANSMISSION AND DISEASE
Overgrowth of G. vaginalis and other bacteria in the female genital tract can disrupt the normal microbiome and lead to bacterial vaginosis.
Antibiotics are effective for treating bacterial vaginosis either topically or orally.
Harper, J; Davis, G (1982). “Cell Wall Analysis of Gardnerella vaginalis”. Int J Syst Bacteriol. 32: 48–50. doi:10.1099/00207713-32-1-48.
Ferris, D.G.; Litaker, M.S.; Woodward, L.; Mathis, D.; Hendrich, J. (1995). “Treatment of bacterial vaginosis: a comparison of oral metronidazole, metronidazole vaginal gel, and clindamycin vaginal cream”. The Journal of Family Practice. 41 (5): 443–449. PMID 7595261.