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STRUCTURE AND PHYSIOLOGY
S. saprophyticus is a gram-positive, coccoid, coagulase-negative, non-hemolytic bacteria that is commonly a part of the human microflora in the perineum, rectum, urethra, cervix, and gastrointestinal tract.
TRANSMISSION AND DISEASE
Other than E. coli, S. saprophyticus is one of the most common causative agents in uncomplicated Urinary Tract Infections (UTIs). It can also be responsible for more serious complications such as urethritis, epididymitis, and prostatitis.
S. saprophyticus can be difficult to eliminate due to its ability to readily adhere to surfaces and subsequently form biofilms. This results in the fast-paced development of antibiotic resistance.
Alteration of the vaginal flora, such as spermicides and candidal infection, can increase the likelihood of infection by S. saprophyticus.
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