STRUCTURE AND PHYSIOLOGY
Shigella sonnei is a Gram-negative, rod-shaped, nonmotile, non-spore-forming bacterium and has historically been responsible for causing dysentery. S. sonnei is highly clonal (genetically identical cells), and a selective group of lineages is found worldwide.
TRANSMISSION AND DISEASE
S. sonnei causes the disease shigellosis, an intestinal infection that is spread through contact with infected stool. Contact with contaminated food or water increases the likelihood of infection, and common symptoms include fever, abdominal pain, nausea, and diarrhea. Severe infection can lead to bacteremia and be life threatening.
Antibiotic-resistant strains of S. sonnei have been identified. Clinical samples were found to be multi-resistant to ampicillin and trimethoprim-sulfamethoxazole.
Two strains of Shigella sonnei are referenced as required microorganisms on the FDA’s 2016 Consumer Antiseptic Rub proposed rule (81 FR 42912 at 42921).
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