cosmetic

Towelette Preservative Challenge Test For Cosmetics

Many cosmetics and personal care products are now available in the form of pre-saturated towelettes or wipes. Like the majority of personal care products having an aqueous base, pre-saturated towelettes are susceptible to microbial contamination and require a preservation system to protect them from degradation. Cosmetics and personal care...

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USP <51> – Preservative Challenge Test

Introduction The USP Chapter 51 Preservative Challenge Test is the most common method used to gauge preservative effectiveness.  Much like a Preservative Challenge Screen, it is used to evaluate the effect of preservatives in cosmetics, personal care products, and drug products. Preservatives are antimicrobial ingredients that are added to aqueous...

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USP <61> – Microbial Enumeration Test

The USP <61> - Microbial Enumerations Test is a product safety test found in Chapter 61 of the United States Pharmacopeia. It is suggested for use by the FDA for pharmaceuticals as well as cosmetics and personal care products to ensure that a product's preparation complies with pre-set specifications...

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USP <62> – Test For Objectionable Microorganisms

The USP <62> Test for Specified Microorganisms, like the USP <61>, is a product safety test from the United States Pharmacopeia. The USP <62> test evaluates a product for the presence or absence of potential pathogens. USP <62> tests are necessary for cosmetic and personal products to determine that any...

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PCPC (formerly CTFA) Test Methods for Cosmetics

Cosmetics and personal care products are perfect environments for microorganisms to grow unless proper measures are taken during formulation and manufacture to preserve them. Cosmetics and personal care products are intended for use in direct contact with the body and this makes it imperative for these products to be...

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Photostability Testing

Cosmetic and personal care products may be exposed to many different conditions throughout their life cycle. When considering a stability testing regimen, it is necessary to try to replicate the conditions that they are most likely to experience during their transport, storage and use. When we go outside and our bodies are...

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Preservative Challenge Quick Test

Preservative Challenge "Quick Test": Procedure at a Glance Antimicrobial preservatives are substances added to non-sterile products to protect the product from microbiological growth that may be inadvertently introduced during the manufacturing process. In this study, the test demonstrates the effectiveness of the antimicrobial protection.  For the preservative challenge "quick test," the...

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Preservative Challenge Screen

Preservative challenge testing is a fast and easy way to learn about the efficacy of your preservative system. Preservatives are ingredients used to protect a product from deterioration and help it perform as intended for the lifetime of the product. The efficacy of a preservative depends on the combination of the product's...

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Preservative Challenge Test

USP 51: Procedure at a Glance The Antimicrobial Effectiveness test method or USP 51 utilizes the following microorganisms Candida albicans (ATCC No. 10231), Aspergillus niger (ATCC No. 16404), Escherichia coli (ATCC No. 8739), Pseudomonas aeruginosa (ATCC No. 9027), and Staphylococcus aureus (ATCC No. 6538). The test product is inoculated with...

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Realtime Aesthetic Stability Test

Realtime Aesthetic Stability Testing is very similar to the accelerated aesthetic test in that it tests for all the same characteristics, however products tested in realtime are stored at room temperature or the product's recommended storage conditions for the full length of shelf life testing. Accelerated Testing is commonly used to screen...

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Freeze-Thaw Stability Testing

During transportation of cosmetic products, it is not uncommon for them to encounter extreme temperature conditions, such as freezing or overheating. Thus, it is necessary for cosmetic products to be able to withstand a certain degree of temperature changes in transport. Freeze-thaw cycle testing is a part of stability testing that allows...

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ISO 11930 – Preservative Effectiveness Test

The ISO 11930 - Preservative Challenge Test is a procedure for evaluating the antimicrobial protection of a product. Much like the USP <51>, it evaluates the activity of preservatives or other intrinsic characteristics of a product that help maintain the safety of a product by inhibiting the growth and...

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Ocular Irritation Test

The Ocular Irritation Test, much like the Dermal Irritation Test, uses a 3-dimensional model of eye tissue to determine the potential of a cosmetic product or ingredient to cause eye irritation when used by the consumer. Just as some cosmetic products can cause irritation to the skin, they can cause similar effects to the...

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Package Compatibility Testing

When testing a cosmetic or personal care product for shelf-life and stability, packaging is a major factor that should be taken into consideration. While the product itself may have a relatively stable shelf-life when tested in glass or another temporary package, the same stability may not be observed in...

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Dermal (Skin) Irritation Test

The Dermal Irritation Test is a test that is used to evaluate the potential of a product to cause skin irritation when used by the consumer. Some cosmetic products can cause skin irritation by passing through the outer layer of the skin (called the stratum corneum) and enter the layers beneath...

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Dermal and Ocular Corrosion Testing

Dermal Corrosion Dermal corrosion is the production of irreversible scarring usually as a result of corrosive tissue damage following the application of a substance. Dermal corrosion results from skin penetration of a chemical or ingredient causing death to the cells beneath the skin surface. Dermal corrosion differs from dermal irritation in that...

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Dermal Sensitization Test

The Dermal Sensitization Test is an in vitro skin model that can assess the potential of virtually any product to cause dermal sensitization, or more specifically, allergic contact dermatitis. Allergic contact dermatitis (ACD), like most allergic responses, develops in two phases and is dependent on the induction of an immune response. The first...

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Accelerated Physical Stability Testing

Cosmetic and personal care products that are intended for storage at room temperature have two options for stability testing, real-time and accelerated testing. Many people are unaware that stability testing can be performed at an accelerated rate. Accelerated shelf-life testing is based on the idea that a product that...

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Aerobic Plate Count Test: Fungi

Yeast and molds are types of fungal cells that can cause various degrees of deterioration and decomposition of cosmetics and personal care products. Since yeast and molds are ubiquitous (occurring everywhere) in nature just as bacteria are, cosmetics and personal care products are just as susceptible to fungal contamination...

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Aerobic Plate Count: Bacteria

Microbiological contamination of cosmetics and personal care products during the manufacturing and production process is a common concern in the cosmetic industry. The FDA requires that all cosmetics for consumer use be free of filth as well as void of any putrid or harmful substance that could be damaging to...

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